List of the top 20 organizations with the largest IP allocations in Panama
| Rank | Name | IPv4 addresses | IPv6 /64 networks | AS numbers | Prefixes |
|---|---|---|---|---|---|
| Cable & Wireless Panama | 2,679,808 | 1.03 x 237 | 1 | 178 | |
| Cable Onda | 2,200,608 | 1.5 x 233 | 9 | 1,014 | |
| UFINET PANAMA S.A. | 114,176 | 1.39 x 235 | 2 | 482 | |
| 4 | Universidad Tecnologica de Panama | 62,976 | 232 | 1 | 247 |
| 5 | TEFINCOM S.A. | 52,480 | 1.63 x 219 | 2 | 217 |
| 6 | Private Layer INC | 30,464 | 233 | 2 | 16 |
| 7 | Galaxy Communications | 16,128 | 232 | 2 | 37 |
| 8 | Liberty Technologies Corp. | 12,544 | 232 | 1 | 57 |
| 9 | Columbus Networks Panama | 10,752 | 0 | 1 | 21 |
| 10 | Metro MPLS | 9,216 | 232 | 1 | 14 |
| 11 | Trans Ocean Network | 6,656 | 232 | 1 | 26 |
| 12 | Digicel (Panama), S.A | 5,632 | 0 | 1 | 8 |
| 13 | Cyber Cast International, S.A. | 4,864 | 0 | 1 | 19 |
| 14 | GRUPO PANAGLOBAL 15 S.A | 4,864 | 1.13 x 235 | 1 | 20 |
| 15 | Servicios de Tecnologías de Información de Misión Crítica, S.A. | 4,352 | 0 | 1 | 11 |
| 16 | COMUNICACIONES TASION | 3,840 | 0 | 1 | 9 |
| 17 | Smithsonian Tropical Research Institute | 3,328 | 0 | 1 | 3 |
| 18 | Shadwell International Inc | 3,072 | 232 | 1 | 20 |
| 19 | Flyservers S.A. | 3,072 | 229 | 3 | 18 |
| 20 | PaNETma S.A. | 2,816 | 0 | 1 | 8 |