List of the top 20 organizations with the largest IP allocations in Panama
| Rank | Name | IPv4 addresses | IPv6 /64 networks | AS numbers | Prefixes |
|---|---|---|---|---|---|
| Cable & Wireless Panama | 2,466,304 | 237 | 1 | 185 | |
| Cable Onda | 2,236,672 | 1.5 x 233 | 9 | 1,062 | |
| PacketHub S.A. | 266,240 | 1.01 x 227 | 4 | 1,074 | |
| 4 | UFINET PANAMA S.A. | 253,184 | 1.65 x 235 | 2 | 1,352 |
| 5 | Cyberzone S.A. | 72,960 | 1.88 x 219 | 1 | 300 |
| 6 | Universidad Tecnologica de Panama | 63,488 | 0 | 1 | 243 |
| 7 | Private Layer INC | 48,128 | 1.25 x 235 | 2 | 84 |
| 8 | Galaxy Communications | 20,992 | 232 | 2 | 49 |
| 9 | Trans Ocean Network | 18,432 | 232 | 1 | 53 |
| 10 | GRUPO PANAGLOBAL 15 S.A | 12,544 | 1.13 x 235 | 1 | 49 |
| 11 | Liberty Technologies Corp. | 12,544 | 232 | 1 | 57 |
| 12 | Metro MPLS | 11,776 | 232 | 1 | 18 |
| 13 | Columbus Networks Panama | 10,496 | 0 | 1 | 20 |
| 14 | Cyber Cast International, S.A. | 4,864 | 0 | 1 | 19 |
| 15 | Servicios de Tecnologías de Información de Misión Crítica, S.A. | 4,352 | 0 | 1 | 11 |
| 16 | COMUNICACIONES TASION | 3,840 | 0 | 1 | 9 |
| 17 | Flyservers S.A. | 3,328 | 229 | 3 | 18 |
| 18 | Smithsonian Tropical Research Institute | 3,328 | 0 | 1 | 3 |
| 19 | Shadwell International Inc | 3,072 | 232 | 1 | 20 |
| 20 | PaNETma S.A. | 2,816 | 0 | 1 | 8 |